Seminarium wydziałowe – prelegent: dr Tomasz Góral (Uniwersytet Warszawski, Centrum Nowych Technologii) NEW

Zapraszamy na seminarium wydziałowe pt. 

Cryo-EM and ED are driving structural studies at the University of Warsaw

Temat przedstawi dr Tomasz Góral (Uniwersytet Warszawski, Centrum Nowych Technologii).

 
Termin

26.05.2026 (wtorek), godz. 14:15

   
Miejsce

Gmach Technologii Chemicznej
Audytorium im. I. Mościckiego  

  
Seminarium dotyczyć będzie techniki cryo-EM oraz możliwości współpracy z Laboratorium Kriomikroskopii i Dyfrakcji Elektronowej w CeNT UW.

  
In 2019, the University of Warsaw acquired and installed one of the first cryo-electron microscopes in Poland — a 200 kV Glacios microscope equipped with a Falcon 3EC camera and a phase plate system. In the following years, the Cryomicroscopy and Electron Diffraction Core Facility was established, providing structural biologists and chemists with direct access to this groundbreaking, Nobel Prize-winning cryo-EM technology. To date, only three cryo-EM core facilities operating in Poland offer services covering all major cryo-EM modalities.

This seminar presents the current capabilities of our Core Facility and the range of services available to users. We operate under an open-access policy and welcome researchers from national and international academic institutions as well as industry partners. Recent developments include benchmarking single-particle analysis (SPA) reconstruction of GroEL protein in complex with the GroTAC peptide at 2.45 Å resolution, with local resolution reaching 2.2 Å (PDB: 8S32), as well as a 2.27 Å reconstruction of the AbiK bacterial polymerase (PDB: 7R06).

Our research portfolio is further expanded by microcrystal electron diffraction (micro-ED), an additional functionality of the microscope that enables rapid structure determination of small molecules and proteins based on electron diffraction data. So far, we have been the only research facility in Poland to successfully implement this technique and publish several papers with micro-ED data.

We demonstrate that offering all major cryo-EM modalities within a single instrument platform (SPA, cryo-electron tomography, and micro-ED) substantially enhances research potential and opens new opportunities across a wide range of life and material science applications.

   
Dla kogo?  

Udział w seminariach wydziałowych jest obowiązkowy dla doktorantów i dyplomantów.

Wstęp na seminarium jest otwarty dla wszystkich osób zainteresowanych tematyką wystąpienia.